Tampines defeated champions Albirex 5-1 in their last S.League encounter on Wednesday.
Manchester United knocked City out of EFL Cup after beating them 1-0 on Wednesday.
Manchester United face Manchester City in the EFL Cup clash on Wednesday.
Geylang have an outside chance of edging Home and qualifying for the 2017 AFC Cup.
While Albirex have already sealed the S.League 2016 title, Tampines have secured a second-place finish.
Manchester United's two summer signings have made it to the 30-man shortlist of 2016 Ballon d'Or.
Manchester City stars Sergio Aguero and Kevin de Bruyne also made the cut in the initial list of 10 nominees.
Doubts loom large over futures of Tampines stars after management's decision to reduce wage budget.
United boss Mourinho accused Antonio Conte of humiliating him after Sunday's defeat.
Mourinho will return to Stamford Bridge for the first time since he was fired as Chelsea boss in 2015.
Liverpool face West Bromwich Albion in the Premier League clash on Saturday.
Arsenal face Middlesbrough in the Premier League clash on Saturday.
AFC Bournemouth face Tottenham Hotspur in the Premier League clash on Saturday.
Neymar is one of the key players for Barcelona, along with Lionel Messi and Luis Suarez.
Singapore have been winless in their last five matches, which includes four defeats.